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Adjustment Criteria: Decisions on treatment changes depend on the initial deficiency level, neurological symptoms, and how well the patient responds

A patient who presents for AOD-9604 as a perceived "milder" or "more natural" alternative to approved GLP-1 receptor agonists is still a patient who needs a validated depression screen (PHQ-A for adolescents), an Eating Disorder Examination Questionnaire, and a conversation about body image expectations

The dose remains fixed while frequency decreases across the three phases: Note: No trial has studied KLOW dosing as a combination

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