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Gclc w/f or Gclc w/w mice (Gclc WT) and Gclc f/f mice (hereafter referred to as Gclc L-KO) were monitored following tail-vein injection with AAV-TBG-Cre (Fig
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While laboratory findings and observational studies suggest potential benefits against the biological drivers of dementia, results from large clinical trials in people with established Alzheimers are still inconclusive
This was reproduced in a companion experiment with semaglutide and MAR709, another GLP-1/GIP dual agonist
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