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Native human alpha-MSH is the 13-residue parent, Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH, with a methionine at position 4 that is the most oxidation-prone group in the molecule and an all-L backbone that peptidases cleave readily
These results indicate that the inhibition of lipid peroxidation by ferroptosis is effective in preventing UUO-induced TEC ferroptosis
Organic selenium (Se)-containing amino acids, such as selenocysteine and selenomethionine, can provide antioxidant benefits by acting both as direct antioxidants as well as a source of selenium for the synthesis of selenium-dependent antioxidants and repair proteins (e.g., glutathione peroxidases, thioredoxin reductases, methionine sulfoxide reductases) 71
Psychiatry 8:297
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