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Glycocalyx degradation after cardiac arrest and resuscitation in rats induces vascular endothelial adhesion factor (VCAM-1), intercellular cell adhesion molecule-1 (ICAM-1), iNOS, and COX-2 expression, exacerbating neuronal loss, glial activation, and brain edema

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But it could help clinicians optimize therapy for patients who have trouble affording the drugs or who struggle with gastrointestinal issues or other side effects, she says

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