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The peptide has high affinity for copper(II) the binding constant is approximately 10^16 M^-1
with 5 mL yields 6 mg/mL
The review synthesized findings from cell-culture experiments (human dermal fibroblasts, keratinocytes, irradiated fibroblasts), animal models (rats, mice, pigs, dogs), and human cosmetic-science studies of topical formulations
Researchers already knew how insulin was synthesised as a result of the work of Donald Steiner, a biochemist at the University of Chicago
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