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Pregnant and breastfeeding women It is not recommended during pregnancy and should not be used while breastfeeding due to limited safety data
prefer it to levothyroxine despite the fact that it is not technically an FDA-approved treatmentit was already widely used when the FDA began approving drugs in 1938, so it never had to go through the formal approval process
The deprotection of Lys protected with Dde or ivDde protecting groups requires the use of a hydrazine solution, which has a strong reductibility, and easily undergoes a side reaction with an oxidizing group
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