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Furthermore, GLP-1 RA-related NAEs are likely to occur in the early stages of treatment, mirroring the temporal trajectory of psychiatric 19 , gastrointestinal 36 , and ophthalmic 37 AEs associated with these agents, and emphasizing vigilance during treatment initiation phase

(The most common side effects are gastrointestinal discomfort and nausea.) Eventually, if you keep taking GLP1s, you will reach a plateau

However, a pharmacovigilance study using the WHO's global adverse drug reaction database found disproportionate reporting of eating disorder adverse events with all three major GLP-1 medications ( Nishida et al., Clinical Nutrition, 2025 )

Metabolizmadan Beyne Uzanan Yolculuk GLP-1, yemek yedikten sonra barsaklarmzdan salglanan doal bir hormondur