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Of those reporting no SGLT2i use at baseline, increasing numbers of participants started SGLT2i during the trial, with a greater proportion starting SGLT2i in the placebo (approximately 10% at 18 months and approximately 20% at 36 months) than in the semaglutide group (approximately 5% at 18 months and approximately 10% at 36 months

The difference is that GHK-Cu activates it biochemically, systemically, and without requiring physical tissue injury

However, data are scant and controversial, resulting in limited efforts to study the effect of nutritional interventions on GSH status