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[10] The first amylin analogue to reach the clinic, pramlintide, demonstrated that the pathway could be drugged, but native-style amylin analogues are short-acting and were used as multiple-daily injections, which limited their appeal for weight management
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All mice that were subjected to an HFD had a higher fat mass compared to the LD control group at the start of the study
PubMed Gwyer, D., Wragg, N.M., Wilson, S.L
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