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A team of researchers developed a nanostructure-based GLP-1R agonist capable of crossing the BBB that significantly attenuated neuroinflammation and memory loss in an A peptide-induced mouse model of AD by inhibiting the inflammatory responses of microglia and astrocytes (Zhao et al., 2022)
Consistent with the literature, VEGF expression was linked with T4 expression, such that in T4-overexpressing mice, VEGF expression was increased and, in T4 KO mice, VEGF expression was reduced
The supplement is also free of undesirable ingredients like magnesium stearate
doi: 10.1126/scitranslmed.abb3774 57 CopinJ.-C.GascheY.ChanP
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