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Splitting ALA into smaller doses may help reduce gastrointestinal side effects, especially at higher intakes.43 Taking ALA with food can also improve tolerability though some studies suggest it may slightly reduce absorption.13 44 That tradeoff may be worth it for users sensitive to GI effects, particularly when taking ALA long-term

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Case report: amelioration of severe metabolic dysfunction-associated steatohepatitis after switching from conventional GLP-1RAs to tirzepatide

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