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Gpx has been shown to degrade lipid hydroperoxides to their respective alcohols and free hydrogen peroxide to water [82, 83], hence reducing oxidative damage [81]
(If the patient already has central access, you can give D20W or D50W via central access
A recent pilot study revealed that both PWS and obese patients (n=8 and 11, respectively) who were administered a single 10-g exenatide injection or placebo in a single-blinded, crossover design showed increased satiety, lowered glucose level, and insulinotropic effects [8]
The release rate is tunable by varying the substitution on the phenyl ring, with electron-donating groups accelerating the release at acidic pH
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