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We included preclinical ( in vitro , in vivo ) and human clinical studies on ASD that reported either redox biomarkers and/or clinical outcomes

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Funding This study was supported by a research grant awarded to Baylor University from Kyowa Hakko Bio Co., Ltd

However, various neurodevelopmental disorder conditions, including ASD, may cause steadily high levels of NO in the brain, promoting abnormal SNO of mitochondrial proteins