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Figure 2 Atherosclerosis, a chronic inflammatory disease, may be an ideal environment for the high viral replication capabilities of SARS-CoV-2 in human cells, enhancing hyper-inflammation secondary to immune system dysregulation (Figure 3) that leads to adverse outcomes, as shown in patients with cardiovascular risk factors

These studies dont yet prove causation, but the patterns they reveal are concerning enough to warrant caution

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In contrast, specific probiotics can induce the secretion of GLP-1 and indeed ameliorate adipose tissue inflammation (Kim et al., 2025)