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This is an obvious concern given the almost 10-fold increase in the use of once-weekly semaglutide within the last five years [8]
These are unlikely from topical cosmeceutical use but possible with repeated high-dose injectable therapy in susceptible patients
* **In small earlier studies, it was suggested that treatment with a similar type of medication, liraglutide, could result in harm among people with reduced ejection fraction heart failure
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