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27 However, contrary to preclinical findings, human studies indicate that weight loss induced by GLP-1 RAs is primarily due to reduced energy intake rather than increased energy expenditure
Most strategies instead modulate pain transmission and neuroinflammation through neural pathways, producing analgesia and disease mitigation via exogenous stimulation or targeted delivery
Most resolve within the first month as the body adapts to the medication
Common and Usually Self-Limiting Nausea in the first 1 to 3 days after injection, particularly during dose increases
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