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Telogen Effluvium: A Review. Journal of Clinical and Diagnostic Research , vol

As a result, pyridoxine deficiency can lead to relevant neuropsychiatric manifestations, such as reduced neurotransmitter synthesis, depression, epilepsy, premature aging of neurons, paresthesias, cerebrovascular diseases, cognitive impairment and carpal tunnel syndrome (, , , , , ) In contrast, pyridoxine may have therapeutic potential for treating depression or aggressive behavior, since pyridoxine plays a crucial role in the tryptophan-serotonin pathway (, )

So it's not like this just huge bolus just hitting your microbiome

The impact of XLH on their lives diminished as their children aged and began treatment with burosumab, with minimal change noted at EoSG