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In obese patients, the goal of body mass loss is to decrease fat mass because it is the cause of a pro-inflammatory environment responsible for numerous clinical complications associated with the pathology

Samples were vortexed and held on ice (4 C) until the final time point, then vortexed again and centrifuged at 18,200 g for 10 min

This eventually affects absorption of fat soluble vitamins like A, D, E, and even K

However, the efficacy of GLP-1 RAs may be limited, particularly in reducing body weight in people with T2DM, and the occurrence of adverse events such as nausea and vomiting is often influenced by the dosage administered (10, 11)