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Recent studies show that sodium-glucose cotransporter 2 (SGLT2) inhibitors can not only protect the kidneys by reducing blood sugar, improving hemodynamics and reducing proteinuria (Martinez Leon et al., 2026), but also inhibit ferroptosis by restoring iron homeostasis, limiting lipid peroxidation and enhancing antioxidant systems (Tsai et al., 2025)
Higher NAD enhances SIRT1 activity, promoting fat oxidation and mitochondrial remodeling via PGC-1 pathwaysmechanisms consistent with improved endurance and recovery potential (Cant et al., Cell Metabolism
While results vary, ALA may offer minor support for weight management, particularly when paired with other lifestyle changes
T., Cymbalisty, C
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