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They work by: reducing appetite increasing feelings of fullness improving blood sugar regulation Because theyre FDA-approved, clinicians have a much clearer understanding of appropriate dosing, common side effects, and long-term safety compared to investigational drugs like retatrutide

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Options include holding the dose and not escalating further, dropping back to the previous dose, switching to the other medication, adding supportive medications for specific symptoms, or in rare cases, discontinuing treatment entirely

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications widely used for type 2 diabetes and obesity