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AB-PAS staining results indicated that, relative to the control group, the CG-LSD model group exhibited impaired gastric mucosal epithelial cell function and a reduction in positive expression (Figure 3B and C)

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The American Diabetes Association (ADA) Standards of Care and American College of Physicians (ACP) guidelines support the use of GLP-1 receptor agonists, including dual agonists like tirzepatide, as effective options for glycemic control and weight management

Common side effects of topiramate include: Burning, numbness, or tingling in your feet, hands, face, or mouth (paresthesia) Dry mouth or altered taste Constipation, nausea, or stomach pain Dizziness, drowsiness, or slowed reactions Nervousness Headache Shaking or muscle weakness Nosebleeds Involuntary eye movements Menstrual irregularities Avoid alcohol and other central nervous system (CNS) depressants, such as sedatives and certain pain medications, as they can increase these side effects