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In a retrospective study of 30 patients with HS treated with semaglutide at an average weekly dose of 0.8 mg, there was a reduction in patient-reported flare-ups and a significant improvement in mean DLQI scores
If the observed benefit of GLP-1 receptor agonists disappears or weakens meaningfully when compared with another contemporary metabolic therapy, then the story becomes less about a unique anticancer effect and more about broader metabolic optimization, comparator selection, or residual differences between treatment populations
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