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Pre-existing inborn errors of sulfur-amino-acid metabolism (e.g., homocystinuria) represent an absolute contraindication because parenteral methionine can exacerbate elevated homocysteine concentrations and associated thrombotic risk
This pathway generates pentose sugar for amino acid and nucleic acid synthesis, converting glucose to ribulose-5-phosphate via the pentose phosphate shunt
Research in cell signaling and cell fate reprogramming, as well as in pharmacological strategies that target different steps in gliogenesis and neurogenesis are opening new scopes in the field of neurorepair
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