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Understanding how nutritional strategies and GLP-1 RAs interact with the gut microbial ecosystem may offer novel insights into optimising therapeutic outcomes and mitigating AEs

Understanding how much protein to eat on GLP-1 therapy is essential for preserving lean muscle mass during rapid weight loss

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Therefore, glucagon acts not only to increase glucose production but also to induce lipolysis, fatty acid oxidation, ketogenesis, increase thermogenesis and energy expenditure, bile acid synthesis, and finally induce satiation and reduce food intake [22, 23]