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While the IOM had based B12 needs on the amount required to correct hematological parameters for people with pernicious anemia, the EFSA had almost 20 more years of research to draw on, and concluded that the most suitable approach was basing needs on biomarkers (serum B12, holotranscobalamin, MMA, and homocysteine)

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Conditional knockout studies of GPX4 provided the first evidence of a previously unrecognized form of cell death characterized by unrestrained lipid peroxidation [17]

It is not a general sale product and should be used under pharmacist guidance