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Do not pour it down the drain
Requires careful cardiac monitoring during initial months
A Monte Carlo simulation with 1,000 iterations was implemented, drawing inputs from predefined probability distributions consistent with recommended practice, namely Gamma for costs, Beta for probabilities and utilities, and Normal or Lognormal for relative risks and treatment effects (72)
Other gastrointestinal effects that may occur on the first day or within the initial week include mild abdominal discomfort, bloating, or changes in bowel habits
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