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daily 500mcg targets beta-3 adrenergic receptors in adipose tissue, not osteoblast MAPK signaling | Key Takeaways AOD-9604 for bone repair uses 300mcg daily subcutaneous dosing sustained for 46 weeks, initiated 35 days post-injury during the soft callus formation phase
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Prescription agents (e.g., semaglutide) : Stronger clinical evidence, FDA-regulated, but may carry more systemic side effects
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