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The TRAVERSE study a large randomized trial of 5,000+ men found that testosterone therapy did not increase rates of major cardiovascular events such as heart attack or stroke compared to placebo, even in men with existing heart risk
Melatonin regulates ILC2 function independently of canonical MT1/MT2 receptors In both mice and humans, two canonical melatonin receptors, MT1 ( Mtnr1a ) and MT2 ( Mtnr1b ), have been described (18, 4042), although neither has yet been reported to be expressed on ILC2s
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