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The result is selective apoptosis of FOXO4-high senescent cells, leaving FOXO4-low non-senescent cells intact a selectivity that makes it a uniquely powerful molecular probe for studying the contribution of senescent cell accumulation to tissue dysfunction, ageing phenotypes, and disease biology

Risks and Considerations While the combination of GLP-1 and phentermine can be beneficial, it is crucial to consider potential risks: Side Effect Amplification : Combining these medications may increase the likelihood of experiencing side effects, particularly gastrointestinal issues and cardiovascular effects

Hum Genet 123 , 321332 (2008)