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Better Absorption for Some Individuals: People with certain medical conditions, such as pernicious anemia or gastrointestinal disorders like Crohns disease, might not absorb enough vitamin B12 from food
10.1093/carcin/bgy038 31 SassoliC.PiniA.ChelliniF.MazzantiB.NistriS.NosiD.et al (2012)
Cheap manufacturers produce the bare 37-amino-acid peptide, skip the lipidation, and sell it as "cagrilintide." It weighs right on HPLC but has a half-life closer to the native hormone roughly useless for weekly dosing
Another study identified potential inhibitors through in silico screening, discovering several chemotypes that inhibited NAPRT at micromolar concentrations
