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Certain preclinical investigations indicate GLP-1 may inhibit inflammatory signaling pathways and reduce oxidative stress in joint tissues
Experts say there are plausible albeit unconfirmed explanations, noting for example that GLP-1 medications may interfere with the efficacy of oral contraceptives or increase fertility in women because they help with weight loss
Furthermore, cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with T2DM
In the RTgill-W1 cells, treatment with rotenone led to GSH depletion, while addition of the GSH precursor NAC, significantly reduced rotenone induced ROS production and dell death
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