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The comparison cohort included patients receiving lifestyle intervention alone, defined by documentation of dietary counseling, exercise counseling, face-to-face behavioral counseling for obesity, or medical nutrition therapy, with no previous lifestyle intervention, no prior history of pulmonary embolism, deep vein thrombosis, or superficial vein thrombosis, and no exposure to weight-loss medications included in the query definition

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Using a systematic rotation protocol ensures no single site receives repeated injections

We emphasize the importance of client commitment to a treatment plan that includes regular tirzepatide injections and consistent follow-up appointments