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Ignoring these signalsor overriding them with medicationcan lead to unintended consequences, whether its a resurgence of old symptoms or the emergence of new ones
For example, if you fly from New York to London, your Monday morning becomes Monday afternoon
These drugs are metabolized primarily through proteolytic degradation by peptidases throughout the body, not through hepatic cytochrome P450 enzymes or biliary excretion pathways
PMID 16638633
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