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The growing popularity of dietary supplements is driving this shift, with glutathione, renowned as the master antioxidant and endorsed by dermatologists, becoming a prominent ingredient in many beauty supplements

While these observations remain context-dependent and model-specific, they contribute to ongoing research interest in multi-receptor peptide systems

For example, reduced EAAT2 activity leads to elevated extracellular glutamate concentrations [309, 310], which trigger excessive calcium influx into both neurons and astrocytes

Therefore, future research should further explore the mechanisms of PCD transitions, key regulatory factors, and the influence of the ovarian microenvironment on PCD interactions