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doi: 10.1016/j.molcel.2018.07.009 45 AarrebergLDEsser-NobisKDriscollCShuvarikovARobyJAGaleMJr

Vitamin C is included in the formula

Risk assessment should consider patient age, smoking history, and presence of constitutional symptoms

This rapid reversibility makes the treatment relatively low-risk for trying: if you experience unmanageable symptoms, your healthcare provider can pause therapy and reassess your approach