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Oral melanotic macules An oral melanotic macule, by conventional definition is a focal, well-defined, uniformly coloured oral mucosal hyperpigmentation, less than 1 cm in diameter, of unknown aetiology

If the patient develops symptoms, they should be advised to discontinue their GLP-1 agonist and contact their healthcare professional immediately

Be sure to keep it out of the reach of children

In earlier work, Sekhars group had shown that in healthy adults, the levels of oxidative stress, oxidative damage and glutathione remain stable until people enter their 60s, when oxidative stress and oxidative damage begin to increase and glutathione to decline