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Exhibits important antioxidant and neuroprotective properties by inhibiting the generation of ROS and reducing oxidative burden in Alzheimers disease [20], and it attenuates ROS/lipid peroxidation (LPO) production induced by central nervous system injury, enhances antioxidant protein levels, and suppresses the expression of mitochondrial apoptotic signaling molecules such as Caspase 3 and Bax [21]

The nausea associated with semaglutide is thought to result from both its effects on gastric emptying and its action on central nervous system centers involved in nausea and appetite regulation

GSNO mobilization has also been described in wounded Arabidopsis leaves where GSNO content increased and showed a uniform distribution pattern, whereas, in systemic leaves, GSNO was first detected in vascular tissues and later extended to the parenchyma cells (Espunya et al., 2012)