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10.1016/j.ijcard.2012.04.150

Tirzepatide acts as a dual GIP and GLP-1 receptor agonist, whereas semaglutide targets GLP-1 receptors only

Furthermore, localized renal neoplasia without changes in renal function is neither considered a risk factor for gastroparesis nor grade 1 obesity.( 1 ) Based on the mechanism of action of semaglutide and other drugs in the same class, the most frequent side effects are weight loss and nausea.( 3 ) While there is no scientific evidence that elucidates the perioperative management of patients using semaglutide and other glucagon-like peptide-1 receptor agonists, it is prudent to consider the high risk of pulmonary aspiration in all of these cases, regardless of fasting time

Physical manoeuvres can also interrupt the reflex: Valsalva manoeuvre : Exhale against a closed airway by pinching your nose and closing your mouth while attempting to breathe out gently for 10-15 seconds