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GABAergic System Interaction BPC-157 demonstrates significant interactions with the GABAergic neurotransmitter system, which has implications for both its neurological effects and its gut-healing properties (given the gut-brain axis connection)
Rather than acting within a single pathway, these compounds are studied for their roles across interconnected systems, where inflammatory signaling, tissue adaptation, and immune modulation form a continuous network
No human RCT in IBD or leaky gut has been completed
AOD-9604 was specifically engineered to avoid this: by isolating only the fat-metabolizing fragment of the hGH molecule, research has not shown it to raise IGF-1 or impair glucose tolerance the way full growth hormone or GHRH analogs can
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