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While GLP-1s can be effective in the short term, research consistently shows that bariatric surgery delivers more durable results

In addition, LG could decrease lipogenesis in the liver in times of IR, driving the pathogenesis of non-alcoholic steatohepatitis (NASH) (48)

Here's a brief timeline: Initial Effects: Many individuals start noticing weight loss effects with tirzepatide relatively early in their treatment, but the exact timeframe can vary due to factors like dosage and individual response