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Erythrocytes affect hemostasis and thrombosis by altering blood viscosity, blood flow dynamics, secreting RBC-derived microvesicles, interactions with platelets or endothelial cells, fibrinogen-induced RBC aggregation, activation of blood coagulation factors, direct modulation of thrombin and fibrin formation, or formation of polyhedral-like erythrocytes in thrombi [47,48,49]

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Subsequently, 800 L of upper aqueous layer was centrifugally filtered through a Millipore 5-kDa cutoff filter at 9100 g and 4 C for 120 min to remove proteins

Once injected, it can travel throughout the body and become available to various tissues