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1mL), which can reduce irritation

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Lower tirzepatide doses (510mg weekly) reduce GI side effect burden while still providing meaningful appetite suppression, allowing researchers to maintain protocol adherence without the nausea and vomiting that causes 1015% of subjects to discontinue at higher doses

These may include: Mild redness around the puncture point Temporary swelling due to fluid introduction Tenderness or itching as the tissue responds Minor bruising from the needle piercing small blood vessels These reactions are often temporary and subside on their own