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GLP-1s work best in conjunction with holistic behavioral change programs: Supplementing GLP-1 use with holistic lifestyle and nutrition behavioral change management programs likely achieves the largest and most sustainable clinical benefit and cost savings, and helps overcome adherence challenges

Starting low and escalating gradually produced fewer gastrointestinal side effects than starting directly at a higher dose, which is why the 2mg +2mg-every-4-weeks schedule became the standard escalation approach in the published data

Slowed Gastric Emptying: They slow down how quickly food leaves the stomach, helping you feel full longer

As a result, the potential for harm and misuse is very high