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It provides the primary nutrients known to be necessary for the breakdown of homocysteine into methionine and other metabolites, including vitamin B6 as pyridoxine and pyridoxal-5-phosphate (P5P), vitamin B12 as methylcobalamin, folate as 5-methyltetrahydrofolate (5-MTHF), trimethylglycine (TMG), and L-serine.* It is now enhanced with vitamin B2 as riboflavin-5-phosphate, Setria glutathione, zinc, and increased amounts of activated pyridoxal-5-phosphate.* As a dietary supplement, 1 capsule one or two times daily with meals, or as directed by a healthcare practitioner

McCandless SE, Cassidy SB : 15q11-13 and the Prader-Willi syndrome

Subramanian A, Tamayo P, Mootha VK, et al