The second runs through RAS, RAF, MEK, and ERK1/2, which control cell-cycle entry and satellite-cell proliferation [5]
Frequently used add-on products include DPP-4s (dipeptidyl peptidase-4 inhibitors) such as Januvia (sitagliptin, from Merck & Co., Inc.), and SGLT2s (sodium-glucose co-transporter 2 inhibitors) such as Jardiance (empagliflozin, from Boehringer Ingelheim/Eli Lilly and Co.) and Farxiga (dapagliflozin, from AstraZeneca plc)
A recent Nature publication further showed that a bimodal molecule combining GLP-1 receptor agonism with NMDA receptor antagonism could reverse obesity and hyperglycaemia in rodent models, with targeted effects on hypothalamic and brainstem neuroplasticity (Petersen et al., 2024, DOI)
Think of it as your skins defense shield against damage from pollutants, stress, and daily wear-and-tear