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IGF-1 is a small polypeptide consisting of 70 amino acids that is synthesized and secreted into the bloodstream mainly by the liver and some IGF-1 is acted upon by the kidneys or skeletal muscles in an autocrine or paracrine manner in their own tissues or periphery (7)
When it binds with copper (Cu), it activates enzymes responsible for: connective tissue formation antioxidant defense cellular respiration It also regulates free copper ions to prevent oxidative stress, keeping the system balanced rather than reactive
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