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Moreover, as an adapter protein involved in selective autophagy and a target of NRF2, p62/SQSTM1 competitively binds to Keap1, subsequently promoting NRF2 activation
Cardiovascular disease Low activity levels of the selenoenzymes, glutathione peroxidases (GPx), have been reported in oxidative stress-related diseases, including cardiovascular disease (CVD) (90)
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