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Moreover, dedicated imaging substudies showed marked drops in hepatic fat , often with normalization in participants on higher doses, along with better insulin sensitivity and reduced visceral adiposity
Clinical eligibility follows FDA labeling for Wegovy and Zepbound: BMI 30+ or BMI 27+ with at least one weight-related comorbidity such as type 2 diabetes, hypertension, dyslipidemia, OSA, or cardiovascular disease
These mechanisms underscore its therapeutic potential (99)
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