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275 PrP Sc and other prion-like polypepetides have the interesting properties of being infectious and able to induce the generation of more prion particles when seeded from one CNS region to another or from even from one individual to another either by ingestion via the diet, or via implantation into the CNS for example from surgical instruments or tissue grafts

Scherz-Shouval, R., Shvets, E

Are used during initial loading phases or in patients with higher metabolic demand (active weight loss programs, metabolic dysfunction-associated steatotic liver disease)

However, its high cost, insurance barriers, and ongoing national shortages are challenging for many patients, which makes alternatives an important consideration
