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For example, vitamin E can thin the blood, making it potentially risky to take with blood thinners.17 And artificial vitamin C can cause some types of chemotherapy to work less effectively and even increase your risk of cyanide poisoning.18 Additionally, fat-soluble vitamins (A, D, E, and K) don't get quickly excreted in your urine like water-soluble ones, making it easier to exceed your upper daily limit and cause health problems instead of helping them.19 For example, adults 19 and older who take more than the upper limit of 3,000mcg of vitamin A may experience:20 Headaches Blurred vision Nausea Dizziness Muscle aches Coordination difficulties And, in very severe cases, an excess of vitamin A can even lead to coma or death.20 Puritan's Pride is generally good at not overdosing its vitamins outside of the upper daily limit, but we recommend making sure to double-check